Variation of Echocardiographic Parameters After Red Blood Cell Transfusion in Emergency Department Anemic Patients

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60+
SponsorCentre Hospitalier Universitaire de Nīmes

About this trial

The goal of this interventional study is to asses echocardiographic variations in emergency department's elderly patients receiving red blood cell transfusion. The main questions it aims to answer are :

* is there a modification of echocardiographic parameters after red blood cell transfusion ? * which parameter is the most impacted by red blood cell transfusion ? Participants will have a transthoracic echocardiography before, just after and 15 minutes after red blood cell transfusion.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

patient needing red blood cell transfusion

consent

social protection

Disqualifiers

fluid filing over 500 mL of crystalloids

transfusion in the last hour

Trial design

Design model

Single group

Treatments tested in this trial

  • transthoracic echocardiography

    Diagnostic test

    E wave, A wave, e' and vdi measurement

Treatment groups

116 Participants
are divided into 1 treatment group
Group A: transfused patientsExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

E/A ratio modification

E/A ratio permits to estimate left ventricle pressure

Time frame
Base line, just after and 15 minutes after red blood cell transfusion

Secondary outcomes

1

E/e' ratio modification

E/e' assesses left ventricle diastolic function

Time frame
Base line, just after and 15 minutes after red blood cell transfusion
2

E wave deceleration time

E wave deceleration time is a reflect of left atrium pressures

Time frame
Base line, just after and 15 minutes after red blood cell transfusion
3

Velocity-time Integral (VTI) modification

Aortic velocity-time integral is the reflect of cardiac output

Time frame
Base line, just after and 15 minutes after red blood cell transfusion
4

Lung score modification

Lung score permits to asses if extravascular water is present in lungs

Time frame
Base line, just after and 15 minutes after red blood cell transfusion

Other outcomes

Sponsors and contacts

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