Patients undergoing major non-cardiac surgery may require postoperative mechanical ventilation and transfer from the operating room to the intensive care unit (ICU). This intra-hospital transport phase is critical, as patients may experience changes in respiratory and hemodynamic status, including alterations in oxygenation, ventilation, blood pressure, and heart rate.
During transport, ventilatory support may be provided using different strategies, including manual ventilation with a bag-valve device or mechanical ventilation with a portable ventilator. Although both approaches are commonly used in clinical practice, there is limited evidence comparing their effects on respiratory function, gas exchange, and overall physiological stability during and after transport.
This multicenter, prospective observational study aims to describe current clinical practices in ventilatory support during intra-hospital transport in adult patients undergoing non-cardiac surgery who require ICU admission. The study will also evaluate changes in vital signs, arterial blood gas parameters, and respiratory mechanics, as well as the occurrence of adverse events during transport and postoperative pulmonary complications within the first five days after surgery.
No additional interventions or procedures beyond standard clinical care will be performed. All data will be collected as part of routine clinical practice. The results of this study are expected to improve the understanding of ventilation management during transport and to identify safer and more effective strategies for critically ill postoperative patients.
Intubated patients undergoing general anesthesia for non-cardiac surgery
Requirement for postoperative IMV
Age ≥18 years
Obtained informed consent
Patients undergoing cardiac surgery
Patients receiving preoperative mechanical ventilation prior to surgery.
Intubated adult patients (≥18 years) undergoing general anesthesia (intravenous or mixed) for non-cardiac surgery, requiring transport from the operating room to the ICU for continuation/weaning from IMV in the postoperative period.
Cohort
Prospective
Not listed
Ventilation strategies applied during transport
Describe the ventilation strategies applied during transport from the operating room to ICU of the intubated patients subjected to general anesthesia for non-cardiac surgery requiring continuation of IMV in the postoperative period.
assess changes in vital signs and blood gas analysis in the peri-transport period
assess changes in vital signs (SpO2 in %) in the peritransport period .
assess changes in vital signs and blood gas analysis in the peri-transport period
assess changes in vital signs (EtCO2 mmHg) in the peritransport period .
assess changes in vital signs and blood gas analysis in the peri-transport period
assess changes in vital signs (Blood pressure in mmHg), in the peri-transport period
assess changes in vital signs and blood gas analysis in the peri-transport period
assess changes in vital signs (heart rate in beats per minute) , in the peri-transport period.
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Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva
Lead sponsor
Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Collaborator
