About this trial
The aim of this prospective, investigator-initiated study is to evaluate the diagnostic accuracy and correlations between mopphometric indices: luminal and qualitative parameters assessed by optical coherence tomography (OCT) including minimal lumen area, plaque type, presence of thin cap fibroatheroma and a functional index - angiography based vessel fractional flow reserve (vFFR) among patients with chronic coronary syndrome identified with intermediate grade coronary stenosis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
18 years or older
Chronic coronary syndrome defined as presence of chest pain ranked 2-3 in the Canadian Cardiovascular Society classification or positive ischemia test (exercise test, single photon emission tomography (SPECT)
Intermediate grade coronary stenosis of 40-80% assessed visually in coronary angiography and OCT examination The patient is willing to participate in the study and has provided a written informed consent
Disqualifiers
Acute coronary syndrome
Proximal left main lesion
Ostial right coronary artery lesion
Bypass of the assessed vessel
Trial population
Patients undergoing coronary angiogram due to chronic coronary syndrome with intermediate grade coronary stenosis.
Trial design
Cohort
Prospective
Treatments tested in this trial
vessel Fractional Flow Reserve
Diagnostic testOptical coherence tomography and vessel fractional flow reserve evaluation of coronary arteries with intermediate to severe stenosis.
Treatment groups
Trial outcomes
Primary outcomes
Correlation between vessel fractional flow reserve (FFR) and minimal lumen area within the coronary stenosis
Correlation between vessel fractional flow reserve (FFR) and minimal lumen area within the coronary stenosis
Secondary outcomes
Major adverse cardiovascular events
Major adverse cardiovascular events
Sponsors and contacts
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