Virtual Biopsy Development to Identify Patient's Glioma Grade at the CHU of Poitiers Using Magnetic Resonance Imaging

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorPoitiers University Hospital

About this trial

Glioma is a tumor of the central nervous system. These lesions are sorted with the WHO ranking regarding the tumoral oncotype. The tumoral MRI assessment is the first step before any medical decision. Currently, only anatomical biopsy can give the tumor grade definition and help to define the most adapted treatment.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age≥ 18 years,

Patient with suspected glioma with prior imaging

Subject free, with legal protection guardianship or curatorship;

Enrollment in the French Social Security system;

Disqualifiers

Any contraindication to an MRI examination

Legal protection, namely minors, persons deprived of their liberty by a judicial or administrative decision, persons residing in a health or social establishment, adults under legal protection and finally patients in emergency situations

Pregnant or lactating women, women of childbearing age who do not have effective contraception

Trial design

Design model

Single group

Treatments tested in this trial

  • Diagnostic test

    Diagnostic test

    The intervention occurs only one time (for 2h30), the MRI examination is divided as follow: * Cinicial MRI (50 minutes) * Research MRI (Phosphorus Spectroscopy, Sodium Imaging)

Treatment groups

500 Participants
are divided into 1 treatment group
Group A: Patient's Glioma gradeExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Validation of the virtual biopsy in the context of gliomas through the use of statistical learning algorithms (artificial intelligence) compared to the biopsy.

Evaluate the diagnostic capabilities of artificial intelligence algorithms for virtual biopsy based on sensitivity and specificity

Time frame
The MRI examination (for 2 hours 30 minutes)

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.