Volatile Non-Invasive Biomarkers of Epileptic Seizures
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity College London Hospitals
About this trial
Breath and sweat samples will be collected from people who have been admitted to hospital after a potential seizure and analysed by the team. The researchers then hope to identify a pattern of small molecules that can distinguish seizures from other events, and perhaps determine the severity of the seizure.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients who have been admitted to either University College London's Queen's Square EEG-telemetry unit or Chalfont Centre for Epilepsy, for diagnosis of seizure events.
Patients aged 18 years or above
Disqualifiers
Patients with active infection or who have taken antibiotics within 4 weeks
Patients on immunosuppressive medications
Patients with co-morbidities preventing breath collection
Patients unable to provide informed consent.
Trial population
People with a diagnosis of epileptic or non-epileptic seizures
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Sample Collection
Other interventionPatients will have breath samples collected by blowing into a bag, and sweat samples collected by gauze. These samples will be collected at various timepoints whilst the patients are admitted on the ward.
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Distinguishing epileptic from non-epileptic seizures
To distinguish epileptic from non-epileptic seizures with the detection of volatile organic compounds (VOCs) in breath and sebum samples.
Time frame
3 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
University College London Hospitals
Lead sponsor
Imperial College London
Collaborator
Source ClinicalTrials.gov