Weight Loss and Hunger

ConditionObesity & Overweight

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-55

SponsorUniversity of Ottawa

About this trial

Weight loss is difficult and weight maintenance even worse. The principles of dieting dictate that to maintain weight loss, one has to eat less calories than they did before the diet. However, there is evidence to show that it may be the diet per se and not the weight loss that makes people more hungry and vulnerable to weight regain. This study will explore whether appetite control can be restored to normal levels through an individually tailored increase in calories after weight loss. If supported, the findings from this study could alter the way we view dieting.

Eligibility criteria

Qualifiers

18-55 years of age;

non-smoking;

obese class I-II (30 kg/m2 ≤ BMI < 40 kg/m2);

weight stable (± 2 kg during the 6 months prior to enrollment);

Disqualifiers

have a current diagnosis of an axis 1 psychiatric disorder (i.e. mood, anxiety and eating disorders);

currently use antidepressants, thyroid medication, or any medication that could affect appetite;

have a history of cardiac problems or symptoms suggestive of any cardiac condition;

have a current diagnosis or history of diabetes, confirmed by a measure of HbA1c during the screening visit;

Trial design

Treatments tested in this trial

Exercise
Dietary Intervention

Treatment groups

40 Participants

are divided into 2 treatment groups

Sponsors and collaborators

University of Ottawa

Lead sponsor

Canadian Institutes of Health Research (CIHR)

Collaborator

Source ClinicalTrials.gov