Whether Control of Serum Uric Acid (SUA) Improves Survival After Pancreatic Cancer

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-85
SponsorHepatopancreatobiliary Surgery Institute of Gansu Province

About this trial

This retrospective study aims to analyze the impact of postoperative changes in serum uric acid (SUA) levels on the prognosis of patients undergoing pancreatic cancer resection.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with pathologically confirmed pancreatic cancer (primary)

Patients who underwent Radical resection of pancreatic cancer(Pancreaticoduodenectomy or Distal pancreatectomy)

The postoperative survival time was at least 6 weeks

Disqualifiers

No surgery was performed, or only palliative surgery/ biopsy was performed

Patients who underwent emergency hemodialysis or plasma exchange after surgery

History of gout or long-term urate-lowering therapy, such as allopurinol

Patients are missing follow-up data

Trial population

Radical pancreatic cancer resection patients

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

  • serum uric acid test

    Diagnostic test

    Detect the serum uric acid in blood sample

Treatment groups

168 Participants
are divided into 2 treatment groups
Group A: High serum uric acid1 intervention
Group B: Low serum uric acid1 intervention

Trial outcomes

Primary outcomes

1

Overall survival

Overall survival was defined as the time from diagnosis to death.

Time frame
3-5 years

Secondary outcomes

1

Recurrence-free survival

Recurrence-free survival is the length of time from either the date of diagnosis or the start of therapy for a disease to the date of the first loco-regional or systemic recurrence.

Time frame
3-5 years
2

Cost of hospitalization

The cost of the first hospitalization from admission to discharge.

Time frame
3 months
3

Length of hospital stay

The first day of hospitalization for the first admission to the last day of discharge.

Time frame
3 months
4

Pancreatic fistula

Whether or not pancreatic-intestinal anastomotic leakage occurred at the time of the first hospitalization.

Time frame
3 months

Other outcomes

Sponsors and contacts

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