About this trial
This study aims to further improve and expand the WB-MRI imaging evaluation cohort of axSpA patients to complete dynamic follow-up and condition assessment. Based on the WB-MRI features, the association of WB-MRI signs with disease activity, inflammation, and structural damage will be analyzed. At the same time, in-depth data mining was conducted and machine learning was used to construct a new axSpA disease activity assessment model based on WB-MRI data, and the accuracy and reliability of the model were clearly evaluated in the discovery cohort and validation cohort.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
None
Trial population
Exclusion Criteria: Unable to provide written consent Unable to undergo MRI examination Pregnancy Unable to read and/or write Chinese
Trial design
Case-only
Prospective
Treatments tested in this trial
Whole body MRI
Procedure/SurgeryThese studies will be performed on a 3Tesla (T) MR system (Achieva, Philips Medical Systems) for all patients.
Treatment groups
Trial outcomes
Primary outcomes
WB-MRI imaging characteristics of patients with axSpA.
Compare the correlation between WB-MRI changes and disease activity, disease progression and structural damage at baseline and after 2 years of follow-up.
Secondary outcomes
The correlation between WB-MRI changes and disease activities
To elucidate the correlation between WB-MRI changes and inflammation, structural damage and disease activity in patients with axSpA.
Sponsors and contacts
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