Whole Exome Sequencing of Familial and Pediatric Forms of Vasculitis
ConditionVasculitis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorBenjamin Terrier
About this trial
The FAMILYVASC study is a prospective observational study which will aim to identify susceptibility loci and genes for systemic vasculitis risk in patients with familial or pediatric forms of vasculitis. Genetic analysis based on whole exome sequencing will be carried out through salivary DNA.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Children and adults
Patients with vasculitis, as defined in the Chapel Hill International Classification in its revised version of 2012
Patient information and signed informed consent
Pregnant and breastfeeding women can be included in the study
Disqualifiers
Refusal of consent or inability to obtain consent
Dementia or unauthorized patient, for psychiatric or intellectual failure reasons, to receive information about the protocol and to give informed consent.
Uncooperative patient, or any pathology that could make the patient potentially non-compliant to the study procedures, and patients interned for regulatory or legal reasons.
Trial population
Adult and childhood patients (no age limit) with familial and pediatric forms of vasculitis as defined in Chapel Hill's international nomenclature in its revised 2012 version.
Trial design
Design model
Family-based
Time perspective
Prospective
Treatments tested in this trial
genetic analysis
GeneticSaliva sample collection for genetic analysis
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Identification of susceptibility loci and genes
Time frame
At the moment of enrollmentSponsors and contacts
Click on the lead sponsor to view all of their trials.
Benjamin Terrier
Lead sponsor
French Vasculitis Study Group
Sponsor institution
Source ClinicalTrials.gov