The purpose of the study is to refine, finalize, implement, and evaluate a multi-level intervention aimed at increasing enrollment of Black and Hispanic patients to National Cancer Institute (NCI)-sponsored therapeutic clinic trials at Moffitt Cancer Center.
Community residents: Community residents may engage with various intervention components deployed in the intervention priority zones.
Community Physicians: may engage with various intervention components deployed in the intervention priority zones if they 1) practice medicine in one of the geographic priority zones.
Cancer Center Physicians: may engage with various intervention components if they 1) practice medicine at Moffitt.
Clinical Research Coordinators (CRC): may engage with various intervention components if they 1) work as a CRC at Moffitt and 2) coordinate/pre-screen patients for at least 1 therapeutic clinical trial at Moffitt.
Community residents, Community Physicians, Cancer Center Physicians, Clinical Research Coordinators, and Moffitt patients who do not meet the inclusion criteria.
Parallel
Continuing Medical Education Events (CME)
BehavioralAn engaging 1-hour informational session focusing on topic areas such as implicit bias and emerging evidence from recent cancer clinical trials with CME credit or American Board of Internal Medicine (ABIM) Maintenance of Certification (MOC) points available.
Trial Connect Portal
BehavioralA digital tool to help facilitate rapid referral of patients to clinical trial opportunities at Moffitt.
Clinical Trial Newsletters
BehavioralElectronic/paper newsletters to highlight open trials at Moffitt that will be distributed by email/mail.
Implicit Bias Training
BehavioralA one-hour educational module will cover information on implicit bias to support the recruitment of diverse patients.
Recruitment Dashboard
BehavioralA dynamic dashboard depicting the number of patients recruited to clinical trials by gender, race, ethnicity, age, cancer type, residence in the catchment area, and other key clinical characteristics.
Portfolio Profiler
BehavioralAn interactive dashboard to allow cancer center physicians easily identify gaps in the current clinical trial portfolio that may be contributing to racial/ethnic disparities in trial enrollment.
Eligibility Calculator
BehavioralA digital calculator that will allow for assessment of the potential impact of clinical trial eligibility criteria (e.g., comorbidities, age, lab values) that may disproportionately exclude patients who are Black and Hispanic prior to submission of clinical trial protocols to the Scientific Review Committee.
Clinical Trial Education Sessions (Community Residents Only)
BehavioralAn engaging 1-hour educational session delivered by a community health educator that includes basic information about clinical trials, their importance, myths, need for diversity in the trials process, and resources for finding more information about clinical trials.
ACT WONDER²S Phone-line/Email (Community Residents and Moffitt Patients)
BehavioralA study team member will be available for questions via a dedicated phone-line and email for community residents and Moffitt patients with a return contact within 24-hours.
New Patient Information (Moffitt Patients Only)
BehavioralIncluding CHOICES DA, a web-based tool to improve multiple aspects of decision-making related to participation in cancer clinical trials.
No Intervention
Other interventionControl group with no intervention.
6
Treatment groupsSee each treatment group below.
Enrollment of Black and Hispanic Patients to NCI-sponsored cancer treatment clinical trials
Intervention impact on enrollment rates will be measured by comparing the percentage of Moffitt patients enrolled on NCI-supported treatment trials who are Black or Hispanic between intervention priority zones and the control priority zones.
Referral of Black and Hispanic Patients to Moffitt Cancer Center
Intervention impact on referral rates will be measured by comparing the percentage of patients referred to Moffitt who are Black or Hispanic between the intervention priority zones and the control priority zones.
Community residents in the intervention CAPZ
The number of community residents that attend a CT educational session.
Community physicians in the intervention CAPZ
The number of physicians that attend a CME event.
Cancer Center CRC
The number of CRCs that used at least one of the CT digital tools.
Click on the lead sponsor to view all of their trials.
H. Lee Moffitt Cancer Center and Research Institute
Lead sponsor
National Cancer Institute (NCI)
Collaborator
