Health Trials

Acute Ischemic Stroke (AIS) Related to a Distal Occlusion

2

Review clinical trials related to Acute Ischemic Stroke (AIS) Related to a Distal Occlusion. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

FORWARD: Functional Outcomes in Real-World Treatment And Revascularization of Non-dominant and Distal M2 Occlusions

The objective of this study is to collect safety and effectiveness data on the Penumbra System reperfusion catheters in participants with isolated primary non-dominant and distal M2 occlusions who undergo endovascular mechanical thrombectomy (EVT). Additionally, this study aims to observe characteristics and outcomes of participants treated with medical management (MM) alone and those who receive EVT + MM per current medical practice.

Participants needed: 250
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Penumbra Inc.Updated: Aug 6, 2026Locations: 1
Eligibility criteria

Participant age ≥ 18 [+5]

Any stenosis or occlusion in the ICA origin requiring treatment during the proce... [+6]

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Status: Recruiting

Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke With Occlusion of the M2 Segment of Middle Cerebral Artery

RESCUE-M2O trial is a prospective, open label, blinded endpoint (PROBE), two-arm, randomized, controlled, post-market study to assess the efficacy and safety of endovascular therapy for acute ischemic stroke with occlusion of the M2 segment of the middle cerebral artery.

Participants needed: 200
Trial details
Age: 18-84Biological sex: AllType: InterventionalSponsor: Hyogo Medical UniversityUpdated: Jul 17, 2026Locations: 3
Eligibility criteria

Acute cerebral infarction [+9]

Occlusion of the anterior temporal artery, duplicate M1, or accessory M1 [+10]

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