Health Trials

Acute Lymphoblastic Leukemia Not Having Achieved Remission

2

Review clinical trials related to Acute Lymphoblastic Leukemia Not Having Achieved Remission. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Determining the Mechanisms of Loss of CAR T Cell Persistence

A prospective observational study of pediatric and young adult acute lymphoblastic leukaemia (ALL) patients treated with CD19 chimeric antigen receptor T-cells (CAR-T cells). The study will examine changes in CAR-T persistence over time and causal factors.

Participants needed: 50
Trial details
Age: Up to 25Biological sex: AllType: ObservationalSponsor: University College, LondonUpdated: Aug 7, 2026Locations: 3
Eligibility criteria

Children and young adults (age 25 years or younger) with relapsed/refractory ALL... [+1]

Patients receiving an alternate CD19-directed CAR T-cell product on a clinical t... [+1]

Read more
Status: Recruiting

MB-CART19.1 in Relapsed/Refractory Acute Lymphoblastic Leukemia

Single-arm, prospective, open-label feasibility study evaluating the technical and operational feasibility of manufacturing autologous CD19-directed CAR-T cells (MB-CART19.1) at the point of care for the treatment of relapsed or refractory B-ALL in pediatric and adult patients.

Participants needed: 12
Trial details
Age: 1+Biological sex: AllType: InterventionalSponsor: King Hussein Cancer CenterUpdated: Aug 5, 2026Locations: 1
Eligibility criteria

Age ≥ 1 year as long as if deemed fit by treating investigator [+7]

Rapidly progressive, uncontrolled disease as assessed by the treating physician... [+12]

Read more