Status: Not yet recruiting
Topical Ruxolitinib in Acute Skin GVHD (Graft Versus Host Disease)
The purpose of this study is to see if ruxolitinib, a Janus Kinase (JAK) 1/2 inhibitor, is safe for people who have acute skin graft versus host disease (GVHD) following allogenic hematopoietic stem cell transplantation (HSCT).
Participants needed: 10
Trial details
Phase: Phase 1Age: 2-35Biological sex: AllType: InterventionalSponsor: Children's Hospital Medical Center, CincinnatiUpdated: Sep 8, 2026Locations: 1
Eligibility criteria
Age ≥2 through age 35 years [+4]
Active uncontrolled skin infections. [+2]