Status: Not yet recruiting
Serum Adropin as an Indicator of Endothelial Dysfunction and Disease Severity in Obstructive Sleep Apnea in Obese Patients
1\. Objectives (Aim): To evaluate the role of serum adropin as a potential biomarker of endothelial dysfunction in OSA 1. Compare serum adropin levels between Obese patients with and without OSA. 2. Correlate serum adropin with OSA severity indices including the Apnea-Hypopnea Index (AHI) and Oxygen Desaturation Index (ODI) and cardiovascular complications. 3. Assess the relationship between serum adropin and endothelial dysfunction markers (endothelin-1). 4. Evaluate adropin's predictive ability for endothelial impairment among OSA patients.
Participants needed: 80
Trial details
Age: 20-75Biological sex: AllType: ObservationalSponsor: Aswan UniversityUpdated: Sep 21, 2026
Eligibility criteria
1- Adults aged 20-75 years. 2-obese Patients diagnosed with obstructive sleep ap...
1-Pregnant females 2-Thyroid disorders 3-Autoimmune diseases 4-chronic liver dis...