Adult Spinal Deformity Surgery

2

Review clinical trials related to Adult Spinal Deformity Surgery. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

SALVAGE Trial (Safety And cLinical Value of AutoloGous rEinfusion)

The investigator hypothesizes intraoperative salvaged red blood cells are a poor substitute for allogenic packed red blood cell transfusions. In addition to providing inadequate resuscitation, salvaged red blood cells can increase the rate of complications, including postoperative electrolyte abnormalities, thrombocytopenia, anemia, and coagulopathy.

Participants needed: 146
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Mayo ClinicUpdated: Jul 17, 2026
Eligibility criteria

Patients >18 years of age undergoing adult thoracolumbar spinal deformity surger...

Patients with active spinal infection, neoplasm, acute trauma, neuromuscular eti...

Status: Recruiting

Post-Operative Thoracolumosacral Orthosis for PJK

Proximal junctional kyphosis (PJK) is a common post-operative radiographic finding after surgery for adult spinal deformity (ASD) patients. Although the clinical relevance of isolated PJK is unclear, PJK can progress to symptomatic proximal junctional failures which requires a large revision surgery. Currently, post-operative bracing with a thoracolumbosacral orthosis (TLSO) is common practice after spinal deformity surgery, however the efficacy of this in preventing PJK is unknown. This multi-center randomized control trial identified 84 patients undergoing thoracolumbosacral fusion for ASD and plans to study the efficacy of a novel post-operative TLSO in preventing the development of PJK as defined by the proximal junctional angle on 6-month post-operative X-rays.

Participants needed: 84
Trial details
Phase: Phase 4Age: 30-75Biological sex: AllType: InterventionalSponsor: Hospital for Special Surgery, New YorkUpdated: Feb 13, 2026Locations: 6
Eligibility criteria

30-75-years-old [+1]

Osteoporosis (defined as a T-score <-2.5 at the time of surgery) [+5]