Status: Recruiting

Phase 3 Randomized Trial for Refractory ADV or CMV Infection With Family Matched CTLs and Standard of Care (SOC) vs SOC Alone

Patients with refractory ADV or CMV infection post allogeneic stem cell transplant will be randomized to either Family donor-derived viral specific cytotoxic T lymphocytes (CTLs) plus standard of care (SOC) vs SOC alone.

Participants needed: 138

Trial details

Phase: Phase 3Age: 1-30Biological sex: AllType: InterventionalSponsor: New York Medical CollegeUpdated: Sep 11, 2026Locations: 2

Eligibility criteria

Consent: written informed consent given (by patient or legal representative) pri... [+8]

Patient with acute GVHD > grade 2 or moderate or extensive chronic GVHD at the t... [+8]

AdV Reactivation

Phase 3 Randomized Trial for Refractory ADV or CMV Infection With Family Matched CTLs and Standard of Care (SOC) vs SOC Alone