Advanced / Metastatic Solid Tumor

2

Review clinical trials related to Advanced / Metastatic Solid Tumor. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of ABO2102 in KRAS-Mutated Solid Tumors

This is a multicenter, open-label Phase 1 clinical study to evaluate the safety, tolerability, immunogenicity, pharmacokinetic (PK) and pharmacodynamic (PD) characteristics, as well as preliminary anti-tumor activity of ABO2102 as monotherapy and in combination among participants with solid tumors with KRAS mutations.

Participants needed: 101
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Suzhou Abogen Biosciences Co., Ltd.Updated: Apr 6, 2026Locations: 1
Eligibility criteria

≥18 years of age at time of informed consent. [+5]

Any other prior malignancy active within the previous 5 years, except for skin b... [+9]

Status: Recruiting

A Study of SR-8541A (ENPPI Inhibitor) in Advanced/Metastatic Solid Tumors

This is an open-label, dose-escalation, multi-center phase 1 study evaluating the safety, tolerability, and pharmacokinetics (PK) of SR-8541A administered orally as a monotherapy or in combination with an immune checkpoint inhibitor (ICI) in subjects with solid tumors.

Participants needed: 25
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Stingray TherapeuticsUpdated: Jun 8, 2025Locations: 3
Eligibility criteria

Life expectancy of at least 3 months [+5]

Primary central nervous system (CNS) tumor [+17]