Advanced Solid Tumors With MTAP Deletion

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Review clinical trials related to Advanced Solid Tumors With MTAP Deletion. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Phase Ia/Ib Clinical Study of GH56 Capsules in Subjects With MTAP-Deleted Advanced Solid Tumors(G-MAP 101)

This is a multicenter, single-arm, open-label, dose-escalation, dose-expansion study to evaluate the safety, tolerability, PK/PD, and preliminary anti-tumor activity of GH56 Capsule in subjects with advanced solid tumors who have failed or are intolerant to standard treatment, or have no standard therapy. The clinical trial will be carried out in two parts: phase Ia study (dose escalation study) and phase Ib (dose expansion study).The Part Ib dose expansion study includes adult cohort and adolescent cohort (12-17 years of age).

Participants needed: 200
Trial details
Phase: Phase 1Age: 12+Biological sex: AllType: InterventionalSponsor: Suzhou Genhouse Bio Co., Ltd.Updated: Oct 2, 2026Locations: 25
Eligibility criteria

Willing to participate in the clinical trial, understand and sign the informed c... [+8]

Subject has not recovered from a prior surgical procedure or has undergone any m... [+7]