Advanced Stage Solid Tumors

2

Review clinical trials related to Advanced Stage Solid Tumors. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of JNJ-89862175 for Treatment of Advanced Solid Tumors

The purpose of this study is to determine safe and effective dose (recommended phase 2 doses \[RP2Ds\]) of JNJ-89862175 in Part 1 (dose escalation), and to further evaluate how safe JNJ-89862175 is at the RP2Ds in Part 2 (dose expansion) in participants with advanced stage solid tumors.

Participants needed: 360
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Janssen Research & Development, LLCUpdated: Sep 28, 2026Locations: 6
Eligibility criteria

Participants must have histologically or cytologically confirmed, metastatic or... [+2]

Active central nervous system (CNS) involvement unless clinically stable [+4]

Status: Recruiting

A Study of JNJ-95437446 in Participants With Advanced-Stage Solid Tumors

The purpose of this study is to determine recommended phase 2 doses (RP2Ds) of JNJ-95437446 in Part 1, and to further evaluate the safety of the RP2Ds in participants with advanced solid tumors in Part 2.

Participants needed: 400
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Janssen Research & Development, LLCUpdated: Sep 29, 2026Locations: 10
Eligibility criteria

Participants must have been previously diagnosed with histologically confirmed u... [+4]

Any prior medical history of ILD/pneumonitis, including pneumonitis from anti-PD... [+4]