Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks

Prospective, multicenter, randomized, double-blind, parallel group, placebo- controlled, efficacy and safety phase 3 study of an intravenous human plasma- derived C1 esterase inhibitor (C1-INH) concentrate in participants with congenital C1-INH deficiency for the treatment and pre-procedure prevention of acute hereditary angioedema attacks

Participants needed: 124
Trial details
Phase: Phase 3Age: 2+Biological sex: AllType: InterventionalSponsor: OctapharmaUpdated: Aug 6, 2026Locations: 23
Eligibility criteria

Is at least 18 years of age (applicable for 1st study phase) or is at least 2 ye... [+14]

Has a history of clinically relevant antibody development against C1-INH [+22]

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Status: Recruiting

A Clinical Trial Evaluating the Safety and Efficacy of AP1189 Versus Placebo as an add-on to Standard of Care in Participants With Respiratory Insufficiency Expected to be Caused by Infection With Respiratory Viruses

A clinical study to evaluate the efficacy and safety of once daily oral dosing of 100 mg AP1189 or placebo administered for 14 days, as an add-on to standard of care (SOC) in participants with respiratory insufficiency expected to be caused by respiratory viral infection.

Participants needed: 96
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: SynAct Pharma ApsUpdated: Jul 28, 2026Locations: 11
Eligibility criteria

Written informed consent has been obtained prior to initiating any study-specifi... [+7]

In the investigator's opinion, progression to death is imminent and inevitable i... [+5]

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