Antineutrophil Cytoplasmic Antibody Associated Vasculitis

2

Review clinical trials related to Antineutrophil Cytoplasmic Antibody Associated Vasculitis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

The primary objective of this study is to evaluate the long-term safety of avacopan in participants with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).

Participants needed: 300
Trial details
Phase: Phase 4Age: 18-100Biological sex: AllType: InterventionalSponsor: AmgenUpdated: Sep 30, 2026Locations: 83
Eligibility criteria

Participants has provided informed consent before initiation of any study-specif... [+5]

Alveolar hemorrhage requiring invasive pulmonary ventilation support anticipated... [+26]

Status: Recruiting

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

This is a Phase 1/2, open-label, multi-center, multi-cohort, non-randomized dose escalation and dose expansion basket study to determine the safety and tolerability of NKX019 (allogeneic CAR NK cells targeting CD19) in participants with autoimmune diseases.

Participants needed: 240
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Nkarta, Inc.Updated: Aug 7, 2026Locations: 18
Eligibility criteria

Age ≥18 and ≤75 [+25]

eGFR < 45 ml/min/1.73m2 [+37]