Arthritis Shoulder

5

Review clinical trials related to Arthritis Shoulder. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Three Year Outcomes After Shoulder Arthroplasty

The purpose of this multicenter observational cohort study is to evaluate three-year outcomes in adults who underwent anatomic or reverse total shoulder arthroplasty using a contemporary shoulder implant system. The main questions it aims to answer are: Are three-year patient-reported outcomes after anatomic total shoulder arthroplasty comparable to those after reverse total shoulder arthroplasty? How often do the implants used during surgery differ from the preoperative three-dimensional (3D) surgical plan, and are these differences associated with patient outcomes, complications, or revision surgery? Researchers will compare patient-reported outcomes, function, complications, and revision rates between patients who underwent anatomic and reverse total shoulder arthroplasty. Researchers will review participant existing medical records and surgical information. Participants whose two- or three-year outcome measures are not available may be asked to complete a one-time questionnaire by telephone or secure electronic survey. No treatments or additional clinical procedures will be performed as part of this study.

Participants needed: 300
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Vani SabesanUpdated: Sep 11, 2026Locations: 5
Eligibility criteria

Primary shoulder arthroplasty [+2]

Revision shoulder arthroplasty [+2]

Status: Recruiting

Zimmer Biomet Shoulder Arthroplasty PMCF Study

This is a multicenter, prospective, non-controlled post market surveillance study. The objectives of this study are to confirm the safety, performance, and clinical benefits of the Zimmer Biomet Shoulder Arthroplasty systems in primary anatomic shoulder arthroplasty and its instrumentation. Safety of the systems will be assessed by monitoring the frequency and incidence of adverse events. The performance and clinical benefits will be evaluated by assessment of the overall pain and functional performance, qualify of life, and radiographic parameters of all enrolled study subjects.

Participants needed: 50
Trial details
Age: 20+Biological sex: AllType: ObservationalSponsor: Zimmer BiometUpdated: Jun 8, 2026Locations: 2
Eligibility criteria

Patient must be 20 years of age or older. [+3]

Patient is unwilling or unable to give consent or to comply with the follow-up p... [+10]

Status: Recruiting

Anatomic TSA vs RTSA for Glenohumeral Arthritis

There are no published prospective studies that compared 2-year functional outcomes of RTSA and anatomic TSA for the treatment of primary glenohumeral osteoarthritis with intact rotator cuffs and no excessive glenoid retroversion. The primary goal of our prospective randomized study is to determine whether RTSA have at least as good results as anatomic TSA (non-inferiority), in patients with glenohumeral osteoarthritis, without rotator cuff tears nor significant glenoid retroversion.

Participants needed: 296
Trial details
Age: 65-85Biological sex: AllType: InterventionalSponsor: La Tour HospitalUpdated: May 22, 2026Locations: 1
Eligibility criteria

Primary glenohumeral arthritis, [+2]

Patients between 65 and 85 years old [+17]

Status: Recruiting

Comparison of Lateralized RTSA With and Without Subscapularis Repair

The purpose of this double-blind randomized controlled trial is to compare patient-reported, clinical, and functional outcomes in patients undergoing RTSA with and without subscapularis repair after placement of a modern "lateralized" implant over the course of 24-months postoperative.

Participants needed: 284
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Panam ClinicUpdated: Feb 25, 2026Locations: 1
Eligibility criteria

Clinical diagnosis of glenohumeral arthritis, rotator cuff arthropathy, or massi... [+3]

Previous shoulder arthroplasty (hemi-, total shoulder, or RTSA) [+9]

Status: Recruiting

Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis(GHOA)

The purpose of this study is to compare the efficacy of intra-articular corticosteroid injections versus platelet-rich plasma injections for non-operative treatment of primary glenohumeral osteoarthritis. The efficacy of intra-articular injections, outside of hyaluronic acid, for the treatment of glenohumeral OA is not known, yet these treatments are commonly used with hopes of providing patients with symptomatic relief that can hopefully delay or prevent the need for shoulder arthroplasty. This study will help elucidate the therapeutic benefit of corticosteroid and Platelet Rich Plasma (PRP) injections in this patient population.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Rush University Medical CenterUpdated: Feb 17, 2026Locations: 1
Eligibility criteria

Patient ≥18y.o. of age [+2]

Secondary causes of arthritis (i.e. septic arthritis, rheumatoid arthritis, rota... [+5]