Attention Deficit Hyperactivity Disorder in Adults

1

Review clinical trials related to Attention Deficit Hyperactivity Disorder in Adults. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

The Effect of 5-hydroxytryptophan on ADHD Traits and Eye Movements

The aim of this project is to look at the impact of 5-Hydroxytryptophan (5-HTP) on distractibility. 5-HTP is the precursor to the neurotransmitter serotonin and is a chemical that the body produces naturally. There is evidence that distractibility is associated with a decreased level of serotonin. This research aims to see if giving people 5-HTP will alter their distractibility, which will form part of an initial assessment as to whether 5-HTP could be used to support people with attention problems. The study involves completing a short survey about mental health and behaviours, and if eligible, participation in an in-person study at the University of Sheffield. The in-person session involves completing some cognitive tasks to look at eye movement, taking 5-HTP or a sugar tablet with no active ingredients, and then completing the tasks again after a 90-minute wait.

Participants needed: 150
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: University of SheffieldUpdated: Aug 20, 2026Locations: 1
Eligibility criteria

18-65 years of age [+2]

Current use of psychostimulant medication or medication for the treatment of ADH... [+7]