Status: Not yet recruiting
26DT052; Scaling Busulfan Dose to Body Surface Area in Children
The goal of this pilot study is to determine if scaling the first busulfan dose to Body Surface Area (BSA) in children with a BSA ≥0.5 m2 and using a BSA-banded dosing table for infants (BSA \<0.5 m2) increases the fraction of patients achieving a therapeutic drug exposure after the first dose.
Participants needed: 38
Trial details
Phase: Phase 1Age: Up to 21Biological sex: AllType: InterventionalSponsor: Children's Hospital of PhiladelphiaUpdated: Aug 28, 2026Locations: 1
Eligibility criteria
Subject age: ≤21 years [+5]