Health Trials

Cardiomyopathy, Hypertrophic Obstructive

2

Review clinical trials related to Cardiomyopathy, Hypertrophic Obstructive. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

BHB-1893 Versus Metoprolol for Symptomatic Obstructive Hypertrophic Cardiomyopathy

The main purpose of this trial is to find out whether BHB-1893 works better than metoprolol in adults with symptoms of obstructive hypertrophic cardiomyopathy (oHCM). The trial includes adults who are currently being treated for oHCM or who have not yet been treated.

Participants needed: 210
Trial details
Phase: Phase 3Age: 18-85Biological sex: AllType: InterventionalSponsor: Braveheart Bio, Inc.Updated: Aug 10, 2026
Eligibility criteria

Diagnosed with oHCM per the protocol specified criteria [+3]

Medical indication for either β-blocker or calcium-channel blocker therapy, othe... [+5]

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Status: Not yet recruiting

IMPACT-CMH: Impact of Mitral Valve and Subvalvular Abnormalities in Obstructive Hypertrophic Cardiomyopathy Treated With Mavacamten

The objective of this observational study is to evaluate the association between the presence of mitral valvular and/or subvalvular anatomical abnormalities prior to initiation of mavacamten and the hemodynamic response at 6 months in patients with obstructive HCM treated with mavacamten. The secondary objective is to determine the impact of different types of anatomical abnormalities of the mitral valve and subvalvular structures on the hemodynamic and clinical response to mavacamten.

Participants needed: 150
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: French Cardiology SocietyUpdated: Jul 21, 2026
Eligibility criteria

Age ≥18 years [+3]

Patients who refuse to participate in this register

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