Cerebral Vascular Accident (CVA)/Stroke

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Review clinical trials related to Cerebral Vascular Accident (CVA)/Stroke. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Self-Supervised Constraint-Induced Movement Therapy for Stroke Recovery

The goal of this clinical trial is to learn how a partially self-supervised constraint-induced movement therapy (sCIMT) program in adults with arm and hand weakness will work after stroke. This study will look at whether the program can help people improve the use of their arm and hand after a stroke while requiring less time with a therapist. The main questions it aims to answer are: * Does the sCIMT program help people use their affected arm and hand better - after a stroke? * Do participants feel that the sCIMT program is useful, easy to follow, and a good fit for their recovery needs? * Does taking part in the sCIMT program improve participants' quality of life and daily well-being? Participants will: * Take part in a therapy program 5x/week for 2 weeks. The program is designed to help improve the use of the arm and hand affected by stroke. * Wear a mitt on the stronger hand during certain practice activities to encourage use of the weaker hand. * Complete surveys and tests before and after the program to measure arm and hand use, experiences with the program, and quality of life.

Participants needed: 12
Trial details
Age: 18-85Biological sex: AllType: InterventionalSponsor: Ohio State UniversityUpdated: Jul 23, 2026Locations: 1
Eligibility criteria

Sustained a first-time ischemic or hemorrhagic stroke ≥2 weeks prior to study en... [+6]

Excessive pain in the affected shoulder, arm, or hand as measured by a score ≥6... [+7]

Status: Recruiting

Evaluation of the Safety and Effectiveness of CHORDS® Cerebral Protection System During TAVR: DUET Trial

This is a prospective, multi-center, randomized controlled study. The goal of the study is to assess the safety and effectiveness of the Resonova® CHORDS® Cerebral Protection System in capturing and removing embolic debris during Transcatheter Aortic Valve Replacement (TAVR). A total of 240 eligible participants will be enrolled and randomized in a 1:1 ratio to undergo TAVR either with the CHORDS® Cerebral Protection System (Test group) or the Sentinel System (Control group).All the participants will be followed up at 30 days and 90 days post-procedure.

Participants needed: 240
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Resonova (Shanghai) Medtech LimitedUpdated: Jun 15, 2026Locations: 15
Eligibility criteria

Male or non-pregnant female, ≥18 years [+3]

Contraindications to MRI, or planned implantation of an MRI-incompatible device... [+8]

Status: Recruiting

The Natural History of Recovery After Stroke

The goal of this longitudinal observational study is to learn the course of recovery after stroke. Specifically, in this study we will learn and describe the changes in cognitive, motor and sensory function over time in stroke patients.

Participants needed: 200
Trial details
Age: 18-85Biological sex: AllType: ObservationalSponsor: Adi Negev-Nahalat EranUpdated: Oct 3, 2025Locations: 3Duration: 1 Year
Eligibility criteria

>18 years of age [+4]

The presence of any degenerative neurological condition, neuropathy, myopathy or... [+4]

Status: Recruiting

Effects of Different Pressure Garments on Upper Extremity Sensorimotor Functions and Quality of Life After Stroke

The study aims to compare the effects of dorsal-double-layered 10% circumferential reduction (DD-10), single-layered 10% circumferential reduction (S-10), and single-layered no circumferential reduction (S-0) pressure garments on sensorimotor functions, including motor control, dexterity, muscle tone, pain, self-perceived upper extremity function, and quality of life among stroke patients during the 8 weeks of application (Time 1: Baseline, Time 2: Week 4, Time 3: Week 8).

Participants needed: 165
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: National University of MalaysiaUpdated: Nov 27, 2024Locations: 3
Eligibility criteria

Between 18 and 80 years of age [+4]

Serious cardiovascular or respiratory diseases [+5]

Status: Recruiting

Error-enhanced Learning & Recovery in 2 & 3 Dimensions

This study is being done to see how errors lead to improvement. Specifically, we are evaluating the errors stroke participants make during an upper extremity exercise program when reaching for a target using their affected arm. Once we understand the participant's reaching errors, we plan to create a customized reaching exercise according to the individual's specific error tendencies which will lead to better performance on movement ability after training.

Participants needed: 20
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Shirley Ryan AbilityLabUpdated: Oct 24, 2024Locations: 3
Eligibility criteria

18 years of age or older [+3]

Bilateral paresis [+18]