Chronic Nonspecific Low Back Pain

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Review clinical trials related to Chronic Nonspecific Low Back Pain. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
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Status: Not yet recruiting

Effects of SIS Therapy in Individuals With Chronic Nonspecific Low Back Pain

Brief Summary - buraya yapıştırın Chronic nonspecific low back pain is a common condition that can cause pain, limitations in daily activities, and reduced quality of life. Exercise and conventional physiotherapy are commonly used to manage chronic low back pain. SIS Therapy is a physiotherapy approach intended to reduce pain and improve movement and function. The aim of this randomized controlled trial is to investigate the effects of SIS Therapy in individuals with chronic nonspecific low back pain and to compare these effects with conventional physiotherapy. Participants will be randomly assigned to one of two groups. The SIS Therapy group will receive SIS Therapy together with a standard exercise program consisting of lumbar stabilization and stretching exercises. The conventional physiotherapy group will receive a program consisting of heat application, transcutaneous electrical nerve stimulation (TENS), therapeutic ultrasound, and therapeutic exercise. Both groups will receive treatment twice a week for four weeks, for a total of eight sessions, and both groups will receive the same home exercise program. Participants will be evaluated before and after the four-week treatment period. The assessments will examine changes in pain intensity, lumbar mobility, and back extensor muscle endurance.

Participants needed: 60
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Pamukkale UniversityUpdated: Sep 24, 2026Locations: 1
Eligibility criteria

Not listed

Status: Recruiting

Is Central Sensitization a Prognostic Indicator in Chronic Nonspecific Low Back Pain?

This observational study will examine whether signs of increased sensitivity in the nervous system at the beginning of the study are associated with short-term clinical outcomes in adults with chronic nonspecific low back pain. Approximately 180 participants will complete questionnaires about central sensitization, disability, pain, anxiety, and depression at the beginning of the study. After 6 weeks, disability, pain, and the participant's overall perception of change will be assessed again. The researchers will evaluate whether the initial level of central sensitization is associated with meaningful improvement in disability and perceived treatment benefit. Participants will not be assigned to a treatment as part of this study and will continue to receive routine clinical care.

Participants needed: 180
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Mardin Artuklu UniversityUpdated: Sep 17, 2026Locations: 1
Eligibility criteria

Adults aged 18 to 65 years [+3]

Progressive neurological deficit [+7]

Status: Not yet recruiting

Sensorimotor Balance Training for Chronic Nonspecific Low Back Pain

Chronic nonspecific low back pain is one of the most common causes of pain and disability worldwide. Many people with chronic low back pain experience difficulties with balance, posture, movement control, and daily activities. Sensorimotor balance training is a rehabilitation approach designed to improve balance, body awareness, and neuromuscular control. The purpose of this randomized controlled trial is to investigate whether sensorimotor balance training is more effective than standard physiotherapy in reducing pain and improving spinal alignment in adults with chronic nonspecific low back pain. Participants will be randomly assigned to either a sensorimotor balance training group or a standard physiotherapy group. Both groups will receive treatment three times per week for 12 weeks. Pain intensity, functional disability, and spinal alignment will be assessed before and after the intervention. Spinal alignment will be measured using the DIERS Formetric 4D system, a non-invasive and radiation-free technology that evaluates posture and spinal shape. The findings of this study may help identify effective rehabilitation strategies for improving pain, function, and spinal alignment in people with chronic nonspecific low back pain.

Participants needed: 80
Trial details
Age: 18-59Biological sex: AllType: InterventionalSponsor: Najran UniversityUpdated: Jun 30, 2026Locations: 1
Eligibility criteria

Adults aged 18 to 59 years. Diagnosis of chronic nonspecific low back pain lasti...

Acute low back injury. History of spinal surgery. Neurological disorders affecti...