Cognitive Benefits

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Review clinical trials related to Cognitive Benefits. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Cardiorespiratory Fitness and Acute High-Intensity Exercise Effects on Brain and Cognitive Function in Older Adults

The goal of this clinical trial is to learn whether a single session of high-intensity interval exercise (HIIT) affects cognitive performance and brain activity in older adults, and whether cardiorespiratory fitness influences these effects. The main questions it aims to answer are: * Does a single HIIT session change performance on a task-switching test of cognitive flexibility? * Does a single HIIT session change prefrontal brain activity during cognitive testing, as measured by functional near-infrared spectroscopy (fNIRS)? * Do older adults with higher cardiorespiratory fitness show greater cognitive and brain changes in response to HIIT than those with lower fitness? Participants will: * Visit the laboratory on two separate days * Complete a sub-maximal graded exercise test during the first visit to measure cardiorespiratory fitness * Complete a single \~30-minute HIIT cycling session during the second visit * Complete a task-switching cognitive test before and after the HIIT session * Have their brain activity monitored with fNIRS while completing the cognitive tests

Participants needed: 50
Trial details
Age: 55-79Biological sex: AllType: InterventionalSponsor: Colby-Sawyer CollegeUpdated: Aug 12, 2026Locations: 1
Eligibility criteria

Physical active in the last three months (>3x/week of 30 minutes of moderate exe... [+2]

Use of illicit drugs, excessive alcohol, and/or performance-enhancing drugs. [+4]