Status: Not yet recruiting
Topical Minocycline for CARP
This proof-of-concept trial evaluates the efficacy, safety, and patient satisfaction of topical minocycline foam (AMZEEQ®) in patients aged 9 and older with confluent and reticulated papillomatosis (CARP). Participants will apply AMZEEQ® to one side of the body and a topical emollient to the other for 5 weeks, followed by an optional extension period. The study aims to assess whether topical minocycline is a well-tolerated and effective alternative to oral antibiotics.
Participants needed: 35
Trial details
Phase: Early Phase 1Age: 9+Biological sex: AllType: InterventionalSponsor: Medical University of South CarolinaUpdated: Jul 21, 2026
Eligibility criteria
Age ≥ 9 years [+1]
Current or recent (within 6 months) use of oral minocycline [+6]