Status: Not yet recruiting
Clinical and Radiographic Evaluation of Subgingival 1% Metformin Gel Versus 0.05% Zoledronate Gel as an Adjunct to MINST of Intrabony Defects in Controlled Type 2 DM
The present randomized placebo-controlled trial aims to evaluate and compare the clinical and radiographic efficacy of subgingivally delivered 0.05% zoledronate gel and 1% metformin gel as adjuncts to minimally invasive nonsurgical treatment of intrabony defects in patients with controlled type 2 diabetes mellitus and periodontitis.
Participants needed: 30
Trial details
Age: 30-60Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Aug 11, 2026
Eligibility criteria
Diagnosed with type 2 diabetes mellitus, with HbA1c levels <7.0% (controlled). [+2]
Smokers. [+4]