Corneal Endothelial Disorder

2

Review clinical trials related to Corneal Endothelial Disorder. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction

This study will evaluate the safety and effectiveness of a single injection of EO2002 at one of two dose levels (150,000 or 500,000 magnetic human corneal endothelial cells \[mHCECs\]), compared with a placebo injection, in participants with corneal edema caused by corneal endothelial dysfunction.

Participants needed: 121
Trial details
Phase: Phase 2Age: 21+Biological sex: AllType: InterventionalSponsor: EmmecellUpdated: Jul 29, 2026Locations: 1
Eligibility criteria

Symptomatic central corneal edema that is primarily responsible for loss of visi... [+4]

Corneal disease in either eye (other than corneal endothelial dysfunction second... [+9]

Status: Recruiting

The Belgian Endothelial Surgical Transplant of the Cornea

This study is designed as a randomised multicentric parallel group pragmatic trial of Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) versus Descemet Membrane Endothelial Keratoplasty (DMEK) in corneal endothelial decompensation. the purpose is to compare the clinical and patient reported outcomes of both therapies across a broad range of indications.

Participants needed: 220
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University Hospital, AntwerpUpdated: Apr 3, 2026Locations: 11
Eligibility criteria

Fuchs Endothelial Dystrophy (FED); [+5]

Inability to provide informed consent; [+8]