Status: Not yet recruiting
Study to Evaluate the Long-Term Safety of Ultevursen in Participants With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene
The purpose of this Phase 2 Open-label study is to evaluate the long-term safety and tolerability of Ultevursen administered via intravitreal injection (IVT) in participants with Retinitis Pigmentosa due to mutations in exon 13 of the USH2A gene. This is a multicenter study which will enroll approximately 81 participants, however, the exact number enrolled will depend on the final number completing the 24-month LUNA trial and are eligible and willing to enroll in CAPELLA.
Participants needed: 81
Trial details
Phase: Phase 2Age: 8+Biological sex: AllType: InterventionalSponsor: Laboratoires TheaUpdated: Sep 1, 2026
Eligibility criteria
Participants who have completed the LUNA study through Month 24 and, in the Inve... [+3]
Treatment Cohort only: New ocular condition in the SE (e.g., severe infection, u... [+5]