Dermatitis, Atopic

12

Review clinical trials related to Dermatitis, Atopic. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A First-in-human Study to Investigate Single Doses of DCY636 in Healthy Volunteers and Multiple Doses in Participants With Moderate to Severe Atopic Dermatitis

The purpose of this first-in-human (FIH) study is to assess the safety and tolerability, pharmacokinetics (PK), immunogenicity (IG) and pharmacodynamics (PD) of DCY636. The results are intended to support the further clinical development of DCY636 in future studies.

Participants needed: 63
Trial details
Phase: Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: Novartis PharmaceuticalsUpdated: Aug 19, 2026Locations: 1
Eligibility criteria

Males and non-pregnant females age 18 years or older [+5]

Use of other investigational drugs within the last 30 days or 5 half-lives of th... [+11]

Status: Recruiting

Real World Efficiency of Abrocitinib Treatment at Patients With Moderate to Severe Atopic Dermatitis Who Had Inadequate Response to Previous Biologic Therapies.

This is a prospective, multi-center observational study characterizing clinical and patient reported outcomes of patients receiving abrocitinib for moderate-to-severe atopic dermatitis (M2S AD) who had inadequate response (or intolerance) to ≤2 previous biologic therapies approved for M2S AD in the United States. The aim of this study is to measure the effectiveness of abrocitinib in a real-world setting in patients with moderate-to-severe atopic dermatitis, with inadequate response or intolerance to ≤2 biologic therapies.

Participants needed: 150
Trial details
Age: 12+Biological sex: AllType: ObservationalSponsor: PfizerUpdated: Aug 17, 2026Locations: 1
Eligibility criteria

Participants who have chronic AD that has been present for ≥1 year before screen... [+9]

Status: Not yet recruiting

Evaluation of 611 in Chinese Children With Moderate to Severe Atopic Dermatitis(AD)

This study is a 2-part (parts A and B) study.The primary objective of the study is to evaluate the efficacy of 611 in Chinese Children with moderate to severe atopic dermatitis (AD).

Participants needed: 246
Trial details
Phase: Phase 3Age: 2-11Biological sex: AllType: InterventionalSponsor: Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.Updated: Aug 17, 2026Locations: 5
Eligibility criteria

The participants and their legally acceptable representatives are able to unders... [+10]

Intolerance to TCS / TCI treatment or contraindications to TCS / TCI; [+17]

Status: Recruiting

A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis

This is a phase 2b, multicenter, randomized, double-blind, placebo-controlled study.

Participants needed: 280
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Apollo Therapeutics LtdUpdated: Aug 12, 2026Locations: 85
Eligibility criteria

Age 18-65 inclusive, at the time of signing the informed consent. [+8]

History or other evidence of severe illness or any other conditions such as psyc... [+32]

Status: Recruiting

Effects of Treatments on Atopic Dermatitis

Background: \- Atopic dermatitis, or eczema, is a chronic skin disorder. Patients sometimes have infections with S. aureus bacteria. Researchers want to study how eczema treatments affect the number and the type of bacteria on the skin. Objectives: \- To study the effect of eczema treatments on skin bacteria. Eligibility: * Individuals between 2 and 25 years of age who have moderate to severe atopic dermatitis. * Healthy volunteers between 18 and 40 years of age with no history of eczema. Design: * Participants will be screened with a physical exam and medical history. Research samples will be collected. Skin biopsies may also be performed. * All participants will be assigned to one of several study groups. * Healthy volunteers must not have taken antibiotics in the year before the start of the study. * All participants will have regular study visits during their 1-year participation. More research samples will be collected at these visits. * Healthy volunteers may be asked to come in for a one-time follow up after the 1 year mark.

Participants needed: 130
Trial details
Phase: Phase 2Age: 2-50Biological sex: AllType: InterventionalSponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)Updated: Aug 7, 2026Locations: 1
Eligibility criteria

Males and females aged 18-50 years at time of initial protocol sampling [+16]

Does not meet inclusion criteria [+47]

Status: Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor

This is a parallel group, Phase 3, multinational, multicenter, randomized, double-blind, placebo-controlled, 3-arm study for treatment of participants diagnosed with moderate-to-severe AD on background TCS who have had inadequate response to prior biologic or oral JAKi therapy. The purpose of this study is to measure the efficacy and safety of treatment with amlitelimab solution for subcutaneous (SC) injection compared with placebo in participants with moderate-to-severe AD aged 12 years and older on background TCS and have had an inadequate response to prior biologic or an oral JAKi therapy. Study details include: At the end of the treatment period, participants will have the option to enter the Long-Term Safety Study LTS17367 (RIVER-AD). The study duration will be up to 56 weeks for participants not entering the long-term safety study (LTS17367 \[RIVER-AD\]) including a 2 to 4-week screening, a 36-week randomized double-blind period, and a 16-week safety follow-up. The study duration will be up to 40 weeks for participants entering the long-term safety study (LTS17367 \[RIVER-AD\]) including a 2 to 4-week screening and a 36-week randomized double-blind period. The total treatment duration will be up to 36 weeks. The total number of visits will be up to 13 visits (or 12 visits for those entering the long-term safety study LTS17367 \[RIVER-AD\] study).

Participants needed: 636
Trial details
Phase: Phase 3Age: 12+Biological sex: AllType: InterventionalSponsor: SanofiUpdated: Jul 2, 2026Locations: 150
Eligibility criteria

Participants must be 12 years of age (when signing informed consent form) [+8]

Skin co-morbidity that would adversely affect the ability to undertake AD assess... [+9]

Status: Not yet recruiting

A Phase III Study of MG-K10 in Adolescents With Moderate-to-Severe Atopic Dermatitis

This is a randomized, double-blind, placebo-controlled, parallel group study to confirm the efficacy and safety of MG-K10 monotherapy in adolescents with moderate-to-severe atopic dermatitis (AD)

Participants needed: 180
Trial details
Phase: Phase 3Age: 12-17Biological sex: AllType: InterventionalSponsor: Shanghai Mabgeek Biotech.Co.LtdUpdated: Apr 20, 2026Locations: 1
Eligibility criteria

Diagnosis of Atopic Dermatitis (AD) per American Academy of Dermatology (2014) c... [+5]

Inability to tolerate venipuncture, or a history of needle phobia or hematophobi... [+13]

Status: Not yet recruiting

Comparative Study of Crisaborole vs. Tacrolimus in Atopic Dermatitis

This study will compare the efficacy and safety of crisaborole ointment with tacrolimus ointment, in the treatment of patients with mild-to-moderate atopic dermatitis.

Participants needed: 30
Trial details
Phase: Phase 4Age: 5-25Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Jan 26, 2026
Eligibility criteria

Patients with diagnosis of AD, according to Hanifin and Rajka criteria. [+3]

Clinically infected eczema. [+4]

Status: Recruiting

A Study to Learn About the Study Medicine (Called Cibinqo) in People With Atopic Dermatitis

The purpose of this non-interventional study is to learn about the safety and effectivness of Cibinqo Tablet for the possible treatment of atopic dermatitis (AD). AD is a long-lasting itchy red rash, caused by a skin reaction. This study is seeking participants who: 1. Are patients with moderate to severe AD who have been waiting to start treatment with Cibinqo 2. Have evidence of a personally signed and dated informed consent document indicating that the patient or their parent(s) or legal guardian, have been informed of all important details of the study Investigators will collect and record the information on each participant's experiences with Cibinqo. This study medicine is a tablet which is taken by mouth. Participants will be observed for about a year. During this time, we will study the experiences of people receiving the study medicine to help us decide if the study medicine is safe and effective.

Participants needed: 1,100
Trial details
Age: 12+Biological sex: AllType: ObservationalSponsor: PfizerUpdated: Dec 9, 2025Locations: 1
Eligibility criteria

Patients with moderate to severe AD who have been determined to start treatment... [+1]

Patients who have previously received Cibinqo Tablet [+8]

Status: Recruiting

Evaluation of 611 in Chinese Adolescents With Moderate to Severe Atopic Dermatitis

The primary objective of the study was to evaluate the efficacy of 611 in Chinese Adolescents with moderate to severe atopic dermatitis.

Participants needed: 180
Trial details
Phase: Phase 3Age: 12-17Biological sex: AllType: InterventionalSponsor: Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.Updated: Nov 18, 2025Locations: 3
Eligibility criteria

The subjects and their legal guardians are able to understand and comply with th... [+9]

Merge other skin comorbidities that may interfere with the research evaluation. [+25]

Status: Recruiting

The Efficacy of 3% Kanuka Oil Versus 1% Hydrocortisone Cream in Patients With Atopic Dermatitis

Atopic dermatitis is a common disease affecting millions worldwide. A common associated symptom in this population is pruritus. We seek to investigate the use of an natural, over-the-counter cosmeceutical to help this population

Participants needed: 60
Trial details
Age: 12-75Biological sex: AllType: InterventionalSponsor: Nexgen Dermatologics, Inc.Updated: Jul 5, 2024Locations: 1
Eligibility criteria

age greater than 12 years, diagnosis of atopic dermatitis for longer than 2 year...

the use of topical or systemic corticosteroids within 28 days of entering the st...

Status: Recruiting

Spanish Academy of Dermatology and Venereology Registry of Atopic Dermatitis Therapy

The Spanish Registry of Systemic therapy in atopic eczema, BIOBADATOP, assesses drug safety and treatment effectiveness as well as treatment impact on quality of life in children and adults with atopic eczema receiving systemic immuno-modulatory therapies in Spanish daily practice. The main objectives are: 1. To assess short and long-term safety of systemic therapies (including phototherapy) for atopic eczema (pharmacovigilance). 2. To assess short and long-term effectiveness of systemic therapies, providing a basis for shared decision making and guidelines. Secondary objectives are: 1. To assess short and long-term safety of topical therapies for atopic eczema. 2. To assess effectiveness of different methods of care, including patient training. 3. To describe atopic dermatitis comorbidities.

Participants needed: 2,500
Trial details
Biological sex: AllType: ObservationalSponsor: Fundación Academia Española de DermatologíaUpdated: Jan 6, 2023Locations: 9Duration: 5 Years
Eligibility criteria

Paediatric and adult patients with atopic eczema who due to the severity of thei... [+2]

Insufficient understanding of the study by the patient and/or parent/guardian. [+2]