Status: Not yet recruiting
Targeted LSAM-Cisplatin Infusion in Gliomas, Evaluation of Response
Open-label, dose-escalating, Phase 1/2a trial of Large Surface Area Microparticle (LSAM)-Cisplatin to treat participants with diffuse midline glioma (DMG), including diffuse intrinsic pontine glioma (DIPG), via stereotactic infusion under intraoperative magnetic resonance imaging (MRI) guidance.
Participants needed: 20
Trial details
Phase: Phase 1, Phase 2Age: 3-21Biological sex: AllType: InterventionalSponsor: NanOlogy, LLCUpdated: Aug 18, 2026
Eligibility criteria
Aged 3 to ≤ 21 years. [+7]
Untreated symptomatic hydrocephalus at the time of consent, has metastatic or di... [+10]