Early Stage Non-small Cell Lung Cancer

2

Review clinical trials related to Early Stage Non-small Cell Lung Cancer. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Study to Assess The Safety and Tolerability of Pumitamig-Based Therapy Administered Before Surgery in Participants With Early-Stage Non-Small Cell Lung Cancer (ROSETTA Lung-220)

The purpose of this study is to assess the safety, tolerability, and surgical feasibility of preoperative Pumitamig-based therapy and other molecules in resectable, Early-Stage Non-Small Cell Lung Cancer

Participants needed: 80
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Bristol-Myers SquibbUpdated: Oct 13, 2026Locations: 50
Eligibility criteria

Participants must have newly diagnosed, previously untreated participants with h... [+2]

Participants must not have unresectable disease, N3 nodal involvement, or any ev... [+7]

Status: Recruiting

Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer

The first phase of this study was an open label, randomized pilot study. Enrollment for this phase is now complete. The second phase is a single arm phase 1 safety study. Patients planned to undergo precision hypofractionated radiation to all sites of oligoprogression will receive vancomycin for 1 week before RT and for 1 month after start of RT, and asked to provide stool and blood samples as outlined in the Safety Trial study table.

Participants needed: 10
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Abramson Cancer Center at Penn MedicineUpdated: Jan 14, 2026Locations: 1
Eligibility criteria

Patients planned to receive Stereotactic Body Radiotherapy (SBRT) to a biopsy-pr... [+23]