Edentulism Complete

5

Review clinical trials related to Edentulism Complete. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Accuracy of Complete-Arch Implant Scans Using Non Calibrated Splinting Scanbodies

This randomized crossover clinical study will evaluate and compare the accuracy and chairside time of two non-calibrated splinting systems, IoConnect and Scan Pro, for obtaining complete-arch implant digital scans. The study will include completely edentulous patients with four well-integrated implants connected to multiunit abutments. Each participant will undergo complete-arch implant scanning using both systems, with the order of the scanning protocols determined by a computer-generated randomization sequence. The digital scans obtained with each system will be compared with a verified conventional implant impression used to establish a reference model. The primary evaluation will focus on the accuracy of the implant scans by assessing linear and angular discrepancies between each experimental scan and the reference model. Chairside time required for the scanning procedures will also be recorded. The study will determine whether differences exist between the two non-calibrated splinting systems in terms of complete-arch implant scan accuracy.

Participants needed: 24
Trial details
Age: 40-70Biological sex: AllType: InterventionalSponsor: Menoufia UniversityUpdated: Oct 13, 2026Locations: 1
Eligibility criteria

Adults aged 18 years or older. [+4]

Fewer or more than four implants in the evaluated arch. [+4]

Status: Recruiting

Nutritional Intervention for Older Adults With Complete Dentures

The purpose of this clinical trial is to test a nutritional intervention. This study helps older adults who wear complete removable dentures improve their health. The main questions the study aims to answer are: * What are the participants life experiences living with complete dentures before the intervention? * Does the intervention improve the diet quality of the participants? * Does the intervention improve nutritional status of the participants? * Does the intervention improve chewing performance and muscle strength? * Does the intervention increase the thickness of the masticatory muscles? * Does the intervention improve stress and muscle health markers in saliva? * Does the intervention improve cognitive performance and oral health-related quality of life? * Does the intervention improve cerebral blood flow? The study will include a total of 40 participants, who will be assigned to two groups. One group of 20 participants will receive the nutritional intervention, while the other group of 20 participants will maintain their usual diet during the study period. This comparison will allow the investigators to assess the effectiveness of the intervention. Participants will: * Take part in a personal interview about their life experience with dentures. * Follow a dietary guide with recommendations on specific food textures for six months. * Receive personalized nutritional counseling and participate in healthy cooking workshops. * Use a custom-built mobile application to access the educational content of the nutritional guide, view instructional videos uploaded biweekly, and receive automated reminder notifications. * Attend clinical follow-up assessments, including chewing performance, muscle assessment, saliva markers, assessment of diet quality and nutritional status, cognitive tests, and oral health-related quality of life. * Complete these assessments at three main time points: baseline, 3 months, and 6 months.

Participants needed: 40
Trial details
Age: 60-80Biological sex: AllType: InterventionalSponsor: Universidad de La FronteraUpdated: Sep 17, 2026Locations: 1
Eligibility criteria

Men and women aged 60 to 80 years. [+6]

Altered salivary flow (hyposalivation or xerostomia) identified via anamnesis an... [+6]

Status: Recruiting

Comparison of Non-Calibrated Splinting Bodies and T-Marker for Complete-Arch Implant Scanning

This randomized crossover clinical trial aims to compare the accuracy and scanning efficiency of two digital techniques for recording implant positions in completely edentulous patients receiving implant-supported full-arch prostheses. Each participant will undergo digital impressions using both a non-calibrated splinting scan body system (IoConnect) with an intraoral scanner and a mobile phone-based photogrammetry system (T-Marker). The order of the two scanning methods will be randomized. The primary outcome is the accuracy (trueness) of implant position recording, assessed by comparing each digital impression with a verified reference model. Secondary outcomes include the time required to complete each digital impression. The findings of this study may help determine whether these digital workflows provide accurate and efficient alternatives for complete-arch implant impressions, thereby supporting clinical decision-making in implant prosthodontics.

Participants needed: 40
Trial details
Age: 20-60Biological sex: AllType: InterventionalSponsor: Menoufia UniversityUpdated: Sep 9, 2026Locations: 1
Eligibility criteria

Adults aged 18 years or older. [+4]

Fewer than four implants supporting the maxillary prosthesis. [+5]

Status: Not yet recruiting

3D Metrology-Based Comparison of Functional Casts Made With Conventional and 3D-Printed Custom Trays

This study will compare the dimensional discrepancies of functional casts obtained using conventional custom trays and 3D-printed custom trays made from PET-G (Polyethylene Terephthalate Glycol) filament. Thirty completely edentulous maxillary patients treated in the Complete Denture Course at the School of Dentistry, University of São Paulo (FOUSP), will be evaluated. Anatomical casts will be obtained, digitized, and used to fabricate conventional or digitally designed and 3D-printed custom trays. Functional impressions will then be made with zinc-oxide eugenol impression paste, and the resulting functional casts will be fabricated in Type III gypsum. The casts will be digitized and compared using 3D metrology software. Measurements will be obtained at standardized anatomical regions, including the bilateral tuberosity regions, incisive papilla, palatine raphe, and four vestibular points.

Participants needed: 30
Trial details
Biological sex: AllType: InterventionalSponsor: University of Sao PauloUpdated: Aug 26, 2026
Eligibility criteria

Patients with stable systemic conditions. [+2]

Recent tooth extraction, defined as extraction within the previous 6 months. [+1]

Status: Not yet recruiting

PRINTOW: Occlusal Wear of Denture Teeth in Digitally Fabricated Complete Dentures

This randomized controlled trial evaluates the occlusal wear of denture teeth fabricated using three digital workflows: 3D-printed denture teeth, CAD/CAM-milled double cross-linked denture teeth, and prefabricated denture teeth. Occlusal wear will be assessed over 24 months using digital superimposition techniques. The study aims to determine whether 3D-printed denture teeth demonstrate superior wear resistance compared to CAD/CAM-milled denture teeth.

Participants needed: 45
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Najla ChebibUpdated: May 13, 2026
Eligibility criteria

Written informed consent provided by the participant [+6]

Contraindications to the medical devices used, e.g. known hypersensitivity or al... [+11]