Health TrialsbyHealthPanel

FGFR Gene Amplification

2

Review clinical trials related to FGFR Gene Amplification. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

Phase 2 Study of TYRA-300 in FGFR3 Altered Low Grade, Intermediate Risk NMIBC

Participants needed: 90
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Tyra Biosciences, IncUpdated: Sep 29, 2026Locations: 48
Eligibility criteria

Participants age ≥18 at time of informed consent and willing and able to comply... [+21]

Current or previous history of muscle invasive bladder cancer [+23]

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Status: Recruiting

Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

A Phase 1 study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamic (PD), and preliminary antitumor activity of TYRA-430 in cancers with FGF/FGFR pathway aberrations, including locally advanced/metastatic hepatocellular carcinoma and other advanced solid tumors.

Participants needed: 125
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Tyra Biosciences, IncUpdated: Sep 23, 2026Locations: 16
Eligibility criteria

Age ≥ 18 years [+18]

Have disease that is suitable for local therapy administered with curative inten... [+16]

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