Germline BRCA-mutated HER2-negative Breast Cancer

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Review clinical trials related to Germline BRCA-mutated HER2-negative Breast Cancer. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Fluzoparib Combined With Camrelizumab for Neoadjuvant Treatment of Embryogenic BRCA Mutation HER2 Negative Breast Cancer: an Open, Single Arm, Multicenter Study

This study is an open-label, single-arm, multicenter clinical study. 64 patients with germline BRCA-mutated HER2-negative early breast cancer are planned to be enrolled and treated with fluzoparib combined with camrelizumab to observe and evaluate the efficacy and safety of neoadjuvant fluzoparib combined with camrelizumab in the treatment of germline BRCA-mutated HER2-negative early breast cancer。

Participants needed: 64
Trial details
Phase: Phase 2Age: 18+Biological sex: FemaleType: InterventionalSponsor: Peking University People's HospitalUpdated: Jul 21, 2026Locations: 1
Eligibility criteria

HER2 negative: IHC 0/1+or IHC2+with no amplification of ISH; [+8]

Tumor related symptoms and treatment [+9]