Hemorrhoids Second Degree

2

Review clinical trials related to Hemorrhoids Second Degree. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Comparing Rectal Artery Embolization and Surgery for Treatment of Bleeding Grade 2 and 3 Internal Hemorrhoids

This Phase II study will compare rectal artery embolization with operative hemorrhoidectomy in adults with symptomatic bleeding grade 2 and 3 internal hemorrhoids. Participants will be randomly assigned to receive one of the two treatments. The study will evaluate how each treatment affects quality of life, symptom improvement, bleeding control, recovery time, and treatment-related side effects. The main question this study is trying to answer is whether rectal artery embolization can provide better short-term quality of life compared with surgical hemorrhoidectomy one month after treatment. The study will also examine whether rectal artery embolization allows patients to return to work and normal activities sooner, reduces hemorrhoid-related bleeding, and has a different rate of treatment-related complications compared with surgery. A total of approximately 102 adult participants will be enrolled at a single academic medical center. The results of this study may help determine whether rectal artery embolization is an effective and less invasive alternative to surgical hemorrhoidectomy for the treatment of bleeding grade 2 and 3 internal hemorrhoids.

Participants needed: 102
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: University of Colorado, DenverUpdated: Sep 28, 2026Locations: 1
Eligibility criteria

Male or female, aged >18 years [+9]

Current use of anticoagulants and/or DAPT [+15]

Status: Not yet recruiting

Traditional Medicine Syndromes in Internal Hemorrhoids: a Cross-Sectional Study

This study aims to investigate the characteristics of Traditional Medicine (TM) syndromes in patients diagnosed with internal hemorrhoids at Le Van Thinh Hospital. Internal hemorrhoids are a common anorectal disorder, and their classification in Traditional Medicine remains inconsistent. The study will examine the prevalence of TM syndromes in patients with internal hemorrhoids and assess the correlation between Goligher's classification and TM diagnoses. The study will follow a cross-sectional observational design with an estimated 178 participants. Eligible patients are 18 years or older, diagnosed with internal hemorrhoids, and willing to participate. The primary outcomes include the prevalence of TM syndromes in internal hemorrhoids, severity classification according to Goligher's scale, and correlation analysis between TM syndromes and clinical severity. The study has received approval from the Institutional Review Board (IRB) of the University of Medicine and Pharmacy at Ho Chi Minh City and will be conducted from December 2024 to April 2025 at Le Van Thinh Hospital, Vietnam.

Participants needed: 150
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: University of Medicine and Pharmacy at Ho Chi Minh CityUpdated: Mar 14, 2025Duration: 18 Years
Eligibility criteria

Patients aged 18 years or older. [+2]

Patients with colorectal cancer or other serious gastrointestinal diseases. [+3]