Hepatic Cell Carcinoma

2

Review clinical trials related to Hepatic Cell Carcinoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis

A total of fifty-five (55) patients with liver cirrhosis will be enrolled in this study to produce and validate dedicated Ga-PSMA-PET/MRI acquisition protocols. The specific hypotheses include: * Ga-PSMA PET/MRI may allow robust and reproducible noninvasive in vivo quantitation of hepatic macro and microhemodynamics in cirrhotic patients * Dedicated simultaneously acquired DWI sequences might quantitate liver fibrosis and improve hemodynamic quantitation. * Ga-PSMA PET/MRI may allow noninvasive and reproducible quantitation of portal venous hypertension and predict its evolution, as well as response to treatments * Ga-PSMA PET/MRI may improve noninvasive and reproducible qualitative and quantitative assessment of liver function, structure, nodules and predict evolution of cirrhosis

Participants needed: 45
Trial details
Age: 18-99Biological sex: AllType: ObservationalSponsor: Massachusetts General HospitalUpdated: Oct 14, 2026Locations: 1
Eligibility criteria

Liver cirrhosis as diagnosed by imaging and/or clinical data, including patholog...

Any contraindication to PET, as in attached screening form [+6]

Status: Recruiting

HRYZ-T102 TCR-T Cell for AFP Positive Advanced HCC and Other Solid Tumors

This is a single arm, open-label, dose escalation clinical study to evaluate the safety and efficacy of HRYZ-T102 TCR-T Cell in patients with AFP positive advanced hepatocellular carcinoma and other solid tumors refractory to prior systematic treatments.

Participants needed: 12
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Shanghai Ruiliyuan Biotechnology Co., Ltd.Updated: Dec 2, 2025Locations: 1
Eligibility criteria

The patient must be willing to sign the informed consent form. [+9]

Toxicity of previous treatment has not been mitigated or ≤ Grade 1 at screening. [+14]