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High Grade Serous Ovarian Carcinoma

2

Review clinical trials related to High Grade Serous Ovarian Carcinoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

Participants needed: 120
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: AstraZenecaUpdated: Oct 8, 2026Locations: 13
Eligibility criteria

Participant ≥ 18 year [+12]

History or planned organ or allogeneic stem cell transplantation. [+11]

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Status: Recruiting

First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, as Monotherapy and in Combination With Anticancer Therapy in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

The goal of this study is to identify a safe and tolerated dose of the orally administered KIF18A inhibitor ATX-295. In addition, this study will evaluate the pharmacokinetics, pharmacodynamics and preliminary antitumor activity of ATX-295 as a monotherapy and in combination with bevacizumab (or a biosimilar) in patients with locally advanced or metastatic solid tumors, including ovarian cancer and lung cancer.

Participants needed: 218
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Accent TherapeuticsUpdated: Sep 29, 2026Locations: 11
Eligibility criteria

Patients with histologically confirmed solid tumors who have locally recurrent o... [+7]

Clinically unstable central nervous system (CNS) tumors or brain metastasis [+7]

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