Status: Recruiting
Trial of 225Ac-DOTATATE (RYZ101) in Subjects With ER+, HER2-negative Unresectable or Metastatic Breast Cancer Expressing SSTRs.
Phase 1b/2 open-label trial of 225Ac-DOTATATE (RYZ101) in subjects with ER+, HER2-negative unresectable or metastatic breast cancer expressing SSTRs.
Participants needed: 64
Trial details
Phase: Phase 1, Phase 2Biological sex: AllType: InterventionalSponsor: RayzeBio, Inc.Updated: Oct 6, 2026Locations: 31
Eligibility criteria
Histologically confirmed, ER+, HER2-negative, locally advanced and unresectable... [+8]
Prior radiopharmaceutical therapy, including radioembolization. [+8]