HPV16/18 Positive

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Review clinical trials related to HPV16/18 Positive. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Investigator-Initiated Study of BBM-C101 Injection in Subjects With HPV16/18 Infection

This is a single-arm, single-center, open-label Investigator-Initiated Trial (IIT) designed to evaluate the safety and efficacy of BBM-C101 Injection in subjects with HPV16/18 infection and histopathologically confirmed ≤ Grade 2 CIN, VIN, VAIN or AIN via colposcopy or anoscopy, with a planned enrollment of 200 subjects. The study consists of three phases: a 4-week screening period, a 52-week treatment/follow-up period, and a 52-week long-term follow-up period. Safety will be assessed based on vital signs, physical examinations, laboratory tests, as well as the number and severity of Treatment-Emergent Adverse Events (TEAEs) and Serious Adverse Events (SAEs) occurring throughout the study.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Tianjin First Central HospitalUpdated: Jul 20, 2026
Eligibility criteria

Confirmed HPV16 and/or HPV18 infection of the cervix, vulva, vagina or anus last... [+1]

Cytology results obtained during screening showing any of the following: adenoca... [+16]