Hydrocephalus in Children

2

Review clinical trials related to Hydrocephalus in Children. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Ultrasound and Photoacoustic Imaging of Hydrocephalus in Pediatric Patients

The goal of this study is to out find out the capabilities and limitations of the combined photoacoustic and ultrasound (PAUS) imaging device for diagnosing hydrocephalus in children. The main questions it aims to answer are: * can PAUS imaging allow for new and better ways to rapidly diagnose hydrocephalus? * Can PAUS imaging be used to confirm that treatments for hydrocephalus are working? PAUS imaging has been FDA approved for other medical conditions, but this is the first study to evaluate it for hydrocephalus detection. Participants will undergo imaging through the anterior fontanelle with the dual-mode PAUS imaging device. Each imaging session will take about 30 to 60 minutes. These sessions will take place once before and once after hydrocephalus treatment, as the participant is willing. In some cases, if a patient is having cerebrospinal fluid removed at the bedside, an additional imaging session will occur to monitor the procedure in real-time, if the participant is willing.

Participants needed: 250
Trial details
Age: 0-3Biological sex: AllType: InterventionalSponsor: Michael McDowellUpdated: Aug 25, 2026
Eligibility criteria

Diagnosis of hydrocephalus by a neurosurgeon [+2]

Age > 3 years [+2]

Status: Not yet recruiting

Efficacy and Cost-Effectiveness of Topical Vancomycin Powder in Preventing Pediatric Ventriculoperitoneal Shunt Infections Across Different Etiologies

Objectives * Primary: * To measure the reduction in VP shunt infection rates using topical vancomycin powder. * Secondary: * To compare efficacy across different Etiological Strata (Congenital, Post-hemorrhagic, post-inflammatory). * To analyze the microbiological profile of failed cases. * To compare the "Time-to-Infection" and shunt survival rates between the study and control groups using Kaplan-Meier analysis. * To evaluate the cost-effectiveness of TVP compared to the standard management and historical AIC data

Participants needed: 164
Trial details
Phase: Phase 4Age: 1-18Biological sex: AllType: InterventionalSponsor: Assiut UniversityUpdated: Apr 23, 2026Locations: 1
Eligibility criteria

Age Range: Paediatric patients from birth (neonates) up to 18 years of age. [+3]

Tumor-related Hydrocephalus: Due to the impact of malignancy, chemotherapy-induc... [+6]