Interstitial Lung Disease Due to Systemic Disease (Telomere Biology Disorder)

2

Review clinical trials related to Interstitial Lung Disease Due to Systemic Disease (Telomere Biology Disorder). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Photon-counting CT Scan vs Standard HRCT Scan in the Identification of Idiopathic Pulmonary Fibrosis

The CT-IPF ANTHEM study is designed to prospectively compare PCDCT to HRCT scan in the identification of specific ILD diagnosis discussed during the multidisciplinary discussion to increase diagnostic confidence and reduce unclassifiable ILD cases.

Participants needed: 156
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Istituto Clinico HumanitasUpdated: Aug 27, 2026Locations: 1
Eligibility criteria

≥ 18 years of age [+4]

Patients with acute exacerbation of ILD [+1]

Status: Recruiting

Nucleoside Therapy in Patients With Telomere Biology Disorders

The goal of this clinical trial is to learn if a combination therapy of deoxycytidine (dC) plus deoxythymidine (dT) is safe in patients with telomere biology disorders. The main questions it aims to answer are: * Is the therapy safe with tolerable side effects in patients with telomere biology disorders? * Are problems with the bone marrow or blood or lungs changed after 6 months of dC+dT treatment in patients with telomere biology disorders? Participants will: * Take study drug by mouth three times daily for 24 weeks * Make approximately 2 visits to Boston Children's Hospital during the 24 weeks: once at the beginning of treatment and once at the end of treatment. * Go to a lab for a blood draw an additional 6 times during treatment. * Have 9 phone calls with a research nurse, including one 4 weeks after treatment ends. * Keep a diary to track doses of study drug that were taken or missed.

Participants needed: 36
Trial details
Phase: Phase 1Age: 1-70Biological sex: AllType: InterventionalSponsor: Suneet AgarwalUpdated: Aug 4, 2026Locations: 1
Eligibility criteria

Age ≥ 1 year and ≤ 70 years [+7]

Participants must not have very severe aplastic anemia necessitating bone marrow... [+9]