Intrathecal Morphine

2

Review clinical trials related to Intrathecal Morphine. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Intrathecal Morphine and Transversalis Fascia Plane Block for Analgesia After Open Inguinal Hernia Repair

Inguinal hernia is a common surgical condition, and open inguinal hernia repair may be associated with significant postoperative pain. Inadequate pain control can delay early mobilization, reduce patient comfort, and increase the need for opioid analgesics. Therefore, effective postoperative pain management is an important component of perioperative care. Several analgesic strategies can be used after open inguinal hernia repair, including systemic multimodal analgesia, neuraxial opioids, and regional anesthesia techniques. Intrathecal morphine can provide prolonged postoperative analgesia but may be associated with opioid-related adverse effects such as nausea, vomiting, pruritus, urinary retention, and respiratory depression. Ultrasound-guided transversalis fascia plane block is a regional anesthesia technique designed to provide analgesia to the inguinal region while potentially reducing systemic opioid requirements. The aim of this prospective, randomized, assessor-blinded, controlled trial is to compare the postoperative analgesic efficacy of intrathecal morphine, transversalis fascia plane block, and spinal anesthesia alone in adult patients undergoing elective open unilateral inguinal hernia repair.

Participants needed: 90
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Atatürk Chest Diseases and Chest Surgery Training and Research HospitalUpdated: Sep 21, 2026Locations: 1
Eligibility criteria

Age between 18 and 80 years [+3]

Patient refusing the procedure [+3]

Status: Recruiting

Intrathecal Morphine Versus Intrathecal Dexmedetomidine Compared to Placebo for Postoperative Pain Relief After Spine Fixation Surgeries

This study aims to compare the efficacy of intrathecal morphine and intrathecal dexmedetomidine in reducing pain following lumbar spine fixation surgeries.

Participants needed: 90
Trial details
Age: 21-60Biological sex: AllType: InterventionalSponsor: Tanta UniversityUpdated: Aug 20, 2026Locations: 1
Eligibility criteria

Aged between 21 and 60 years. [+3]

Patients' refusal. [+6]