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Ischemic Stroke or High-risk TIA (ABCD² ≥ 4)

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Review clinical trials related to Ischemic Stroke or High-risk TIA (ABCD² ≥ 4). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

INtensive liPid-lowering Therapy for Acute High-risk IntracRanial or Extracranial atheroSclerosis -II (INSPIRES-2)

The research team is conducting a randomized, double-blind, placebo-controlled, multicenter clinical study aimed at evaluating the impact of adding Tolecilimab (a PCSK9 inhibitor) to standard lipid-lowering therapy (statins ± ezetimibe) on serum lipoprotein(a) \[Lp(a)\] levels and the risk of stroke recurrence within 90 days in patients with ischemic stroke or high-risk TIA (ABCD² ≥ 4) accompanied by elevated lipoprotein(a) levels (≥30 mg/dL).

Participants needed: 242
Trial details
Age: 35-80Biological sex: AllType: InterventionalSponsor: Beijing Tiantan HospitalUpdated: Oct 8, 2026Locations: 1
Eligibility criteria

Age between 35 and 80 years, regardless of gender. [+3]

Have received or are planned to receive intravenous thrombolysis or endovascular... [+20]

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