Status: Recruiting
Exploring the Feasibility of Cerebrospinal Fluid (CSF) and Blood Plasma Liquid Biopsy in Patients With Metastatic Solid Tumours and Primary Central Nervous System (CNS) Tumours: A Pilot Study
This is a prospective, single-centre feasibility study of CSF ctDNA conducted at the Sunnybrook Odette Cancer Centre (SOCC), Toronto, Canada, including multiple solid tumor, stratified into cohorts according to CNS disease involvement, including leptomeningeal disease (Cohort A), parenchymal brain metastases (Cohort B), and no evidence of CNS metastases (Cohort C).
Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Sunnybrook Health Sciences CentreUpdated: Jul 31, 2026Locations: 1
Eligibility criteria
Patients in Cohort A will have previously untreated or progressing leptomeningea... [+7]
Inability to understand or unwillingness to provide written informed consent (la... [+1]