Health Trials

Limbal Stem Cell Deficiency (LSCD)

2

Review clinical trials related to Limbal Stem Cell Deficiency (LSCD). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Clinical Predictors of Visual Outcome in Patients Affected With Ocular Surface Diseases

This retrospective-prospective study aims to identify the diagnostic parameters most predictive of BSCVA in patients with OSD. Clinical, structural, and biochemical data will be collected from standard-of-care examinations and patient-reported outcome questionnaires. The goal is to determine the most informative biomarkers for visual prognosis, streamline diagnostic workflows, and support individualized management of OSD.

Participants needed: 1,000
Trial details
Biological sex: AllType: ObservationalSponsor: IRCCS San RaffaeleUpdated: Jul 14, 2026Locations: 1
Eligibility criteria

The participant is willing and able to provide written informed consent for stud... [+5]

Change of retinal, optic nerve, or macular pathology that may affect best specta... [+5]

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Status: Available

BRM421 Ophthalmic Solution in Patients With Limbal Stem Cell Deficiency

The goal of this program is to provide patients with Limbal Stem Cell Deficiency access to the BRM421 eye drops. Participants will: * Use BRM421 two times a day for at least 12 weeks * Visit the clinic monthly for checkups and tests

Trial details
Age: 18+Biological sex: AllType: Expanded AccessSponsor: BRIM Biotechnology Inc.Updated: Feb 20, 2026Locations: 1
Eligibility criteria

Adult patients with mild to moderate LSCD who unsatisfied with the standard of c... [+2]

The patients eligible for the BRIM clinical trial(s). [+3]

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