Liver Fibroses

5

Review clinical trials related to Liver Fibroses. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Integrated Diagnostics for Early Diagnosis of Liver Disease

This is an observational study that will explore the hypothesis that by combining data from patients with liver disease with novel blood biomarkers, single nucleotide polymorphism (SNP) analysis and faecal microbiome analysis. The Investigators will improve diagnosis of liver fibrosis compared to the current available diagnostic tools.

Participants needed: 1,200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Manchester University NHS Foundation TrustUpdated: Feb 9, 2026Locations: 1
Eligibility criteria

All patients referred to Community Liver Assessment Clinic. [+2]

Age < 18 years. [+5]

Status: Recruiting

Safety and Efficacy of Atorvastatin v. Placebo on HCC Risk

Prospective randomized, multi-center, double blind placebo-controlled trial to assess the chemopreventive impact of atorvastatin (20 mg oral) vs placebo in up to 60 adults with advanced fibrosis at high risk of developing HCC.

Participants needed: 60
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Raymond ChungUpdated: Sep 23, 2025Locations: 2
Eligibility criteria

Willing and able to provide informed consent [+11]

alpha-1-antitrypsin (A1AT) deficiency, Wilson disease, hemochromatosis, iron ove... [+23]

Status: Not yet recruiting

Zinc Sulphate in Treatment Fibrosis in HBV Patient Receiving Antiviral Therapy

This study aims to investigate the possible safety and efficacy of Zinc sulphate as antifibrotic agent in chronic HBV patient receiving antiviral therapy.

Participants needed: 44
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Tanta UniversityUpdated: Aug 28, 2025
Eligibility criteria

Patients with fibrosis stage (F2&F3) post chronic HBV infection receiving standa... [+1]

Patients with prior history of liver transplantation. [+4]

Status: Recruiting

Liver Damage and Cardiometabolic Disorders in NAFLD

Liver fibrosis is the most important prognostic factor in patients with non-alcoholic factor disease. Clinical and biological condition, as diabetes or mutation for PNPLA3, are well known factors associated with liver fibrosis onset and progression. However, little is known about biochemical factors predicting liver fibrosis evolution in large NAFLD populations.

Participants needed: 2,000
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: University of Roma La SapienzaUpdated: Aug 16, 2019Locations: 1
Eligibility criteria

Patients aged 18 years old or more [+5]

Average daily consumption of alcohol >20 g in women and of >30 g in men (assesse... [+6]

Status: Recruiting

Effect of Some Drugs on Liver Fibrosis

Effect of Some Drugs on Liver Fibrosis

Participants needed: 45
Trial details
Phase: Phase 3Age: 20+Biological sex: AllType: InterventionalSponsor: Sherief Abd-ElsalamUpdated: Dec 10, 2018Locations: 1
Eligibility criteria

chronic hepatitis C

Acute hepatitis [+1]